P3-321: DETECTING THE PATHOLOGY OF LOGOPENIC PROGRESSIVE APHASIA WITH AUTOMATED BRAIN VOLUMETRY: CASE REPORT
نویسندگان
چکیده
منابع مشابه
Degenerative Jargon Aphasia: Unusual Progression of Logopenic/Phonological Progressive Aphasia?
Primary progressive aphasia (PPA) corresponds to the gradual degeneration of language which can occur as nonfluent/agrammatic PPA, semantic variant PPA or logopenic variant PPA. We describe the clinical evolution of a patient with PPA presenting jargon aphasia as a late feature. At the onset of the disease (ten years ago) the patient showed anomia and executive deficits, followed later on by ph...
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The primary progressive aphasias (PPA) are paradigmatic disorders of language network breakdown associated with focal degeneration of the left cerebral hemisphere. Here we addressed brain correlates of PPA in a detailed neuroanatomical analysis of the third canonical syndrome of PPA, logopenic/phonological aphasia (LPA), in relation to the more widely studied clinico-anatomical syndromes of sem...
متن کاملPatterns of longitudinal brain atrophy in the logopenic variant of primary progressive aphasia
The logopenic variant of primary progressive aphasia (PPA) is characterised by impaired sentence repetition and word retrieval difficulties. Post mortem studies, amyloid imaging and CSF tau/Aβ measurements suggest Alzheimer's disease (AD) pathology as the underlying cause. Relatively little is known about patterns of progression in patients with the logopenic variant of PPA. 21 patients (3 with...
متن کاملIdentification of an atypical variant of logopenic progressive aphasia.
The purpose of this study was to examine the association between aphasia severity and neurocognitive function, disease duration and temporoparietal atrophy in 21 individuals with the logopenic variant of primary progressive aphasia (lvPPA). We found significant correlations between aphasia severity and degree of neurocognitive impairment as well as temporoparietal atrophy; but not disease durat...
متن کاملPrimary progressive aphasia: a case report
Primary progressive aphasia is a progressive neurodegenerative disorder characterised by deterioration in language function while other higher centre functions are relatively preserved initially. The diagnosis is made based on clinical presentation, linguistic testing and imaging, both functional and structural. Survival is similar to other dementias and the main form of intervention is speech ...
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ژورنال
عنوان ژورنال: Alzheimer's & Dementia
سال: 2019
ISSN: 1552-5260
DOI: 10.1016/j.jalz.2019.06.3353